Using a principal components analysis of morphological data of 1,759 specimens, we detected that the Bothrops neuwiedi complex (with 12 subspecies) is, actually, comprised of 7 full species, differing mainly by qualitative characteristics.One species was nominal.Five subspecies were elevated to the species level.Bothrops iglesiasi and the remaining
Glioblastoma WHO IV (GBM), the most common primary brain tumor in adults, is a heterogenous malignancy that displays a reprogrammed metabolism with various fuel sources at its disposal.Tumor cells primarily appear to consume glucose to entertain their anabolic and catabolic metabolism.While less effective for energy production, aerobic glycolysis (
Cohesin protease Separase plays a key role in faithful segregation of sister chromatids by cleaving the cohesin complex at the metaphase to anaphase transition.Homozygous deletion of ESPL1 gene that encodes Separase left vent protein results in embryonic lethality in mice and Separase overexpression lead to aneuploidy and tumorigenesis.However, the